Steve Hsu posts on rapid human evolution. The possibility of rapid evolution since the rise of agriculture seems to me the best possible critique of Paleo diets, and of the ancestral health paradigm in general. Why ancestral health in general?
If evolution has occurred since the rise of agriculture, barring coincidence, it has occurred differently in different geographic locations. So an "ancestral health" paradigm would not be as informative as an "ethnic health" paradigm.